For Adults and Kids from 3 years old.
Packaging: 10 pieces.
Antiviral agent. Specifically inhibits in vitro influenza A and B viruses (Influenzavirus A, B), including the highly pathogenic subtypes A (HINl) pdm09 and A (H5N1), as well as other viruses that cause acute respiratory viral infections (SARS) (coronavirus (Coronavirus) associated with severe acute respiratory syndrome (SARS), rhinovirus (Rhinovirus), adenovirus (Adenovirus), respiratory syncytial virus (Pneumovirus) and parainfluenza virus (Paramyxovirus)). According to the mechanism of antiviral action, it belongs to fusion (fusion) inhibitors, interacts with the hemagglutinin of the virus and prevents the fusion of the lipid membrane of the virus and cell membranes. It has a moderate immunomodulatory effect, increases the body's resistance to viral infections. It has interferon-inducing activity - in a study on mice, the induction of interferons was observed after 16 hours, and high titers of interferons remained in the blood up to 48 hours after administration. Stimulates cellular and humoral immunity reactions: increases the number of lymphocytes in the blood, especially T-cells (CD3), increases the number of T-helpers (CD4), without affecting the level of T-suppressors (CD8), normalizes the immunoregulatory index, stimulates macrophage phagocytic function and increases the number of natural killer cells (NK cells). Therapeutic efficacy in viral infections is manifested in a decrease in the duration and severity of the course of the disease and its main symptoms, as well as in a decrease in the frequency of development of complications associated with a viral infection and exacerbations of chronic bacterial diseases. In the treatment of influenza or SARS in adult patients, a clinical study showed that the effect of Arbidol in adult patients is most pronounced in the acute period of the disease and is manifested by a reduction in the resolution of symptoms of the disease, a decrease in the severity of the manifestations of the disease, and a reduction in the elimination of the virus. Arbidol therapy leads to a higher incidence of symptoms on the third day of therapy compared to placebo. 60 hours after the start of therapy, the resolution of all symptoms of laboratory-confirmed influenza is more than 5 times higher than that in the placebo group. A significant effect of the drug Arbidol on the rate of elimination of the influenza virus was established, which, in particular, was manifested by a decrease in the frequency of detection of virus RNA on the 4th day. Refers to low-toxic drugs (LD50> 4 g / kg). It does not have any negative effects on the human body when administered orally in recommended doses.
Composition per capsule: Active ingredient: Umifenovir hydrochloride monohydrate (in terms of Umifenovir hydrochloride) - 100 mg. Excipients: potato starch - 30.14 mg, microcrystalline cellulose - 55.76 mg, colloidal silicon dioxide (aerosil) - 2.0 mg, povidone K 25 (collidone 25) -10.1 mg, calcium stearate - 2.0 mg Hard gelatin capsules No. 1
Indications Prevention and treatment in adults and children: influenza A and B, other acute respiratory viral infections. Complex therapy of recurrent herpetic infection. Prevention of postoperative infectious complications. Combined therapy of acute intestinal infections of rotavirus etiology in children over 3 years of age Contraindications Hypersensitivity to umifenovir or any component of the drug; children under 3 years old. The first trimester of pregnancy. The period of breastfeeding. Precautions: Second and third trimesters of pregnancy .
Dosage and administration
Inside, before eating.
Single dose: for children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg (1 capsule of 100 mg or 2 capsules of 50 mg), over 12 years old and adults - 200 mg (2 capsules of 100 mg or 4 capsules of 50 mg).
For non-specific prevention and treatment of influenza and other acute respiratory viral infections in children and adults:
During the period of the epidemic of influenza and other acute respiratory viral infections: children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg twice a week for 3 weeks.
In direct contact with patients with influenza and other acute respiratory viral infections: children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg once a day for 10-14 days.
Treatment of influenza and other acute respiratory viral infections:
Children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 4 times a day (every 6 hours) for 5 days.
Combined therapy of acute intestinal infections of rotavirus etiology in children older than 3 years: from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, older than 12 years old - 200 mg 4 times a day (every 6 hours) for 5 days .
In the complex treatment of chronic bronchitis, pneumonia, recurrent herpes infection: children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 4 times a day (every 6 hours) for 5-7 days, then a single dose 2 times a week for 4 weeks.
Prevention of postoperative infectious complications: children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, older than 12 years old and adults - 200 mg 2 days before surgery, then 2 and 5 days after surgery.
Pharmacy Vacation Terms
Without a doctor’s prescription.
The product comes with Russian instructions translated into the buyer's language. The product packaging contains Russian letters.
Package picture may be variate.
|The purpose of the medication||Antivirus, Immune System|