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  • Artoxan (Tenoxicam) 20mg 3 vials lyophilizate Artoxan (Tenoxicam) 20mg 3 vials lyophilizate

Artoxan (Tenoxicam) 20mg 3 vials lyophilizate

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Artoxan (Tenoxicam) 20mg 3 vials lyophilizate Oxicams

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$46.00

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Details

Pharmacological action 

Artaxan is an effective non-steroidal anti-inflammatory drug (NSAID) with potent anti-inflammatory, analgesic and less pronounced antipyretic effect. The properties of the drug due to inhibition of both isoforms of the enzyme cyclooxygenase, which leads to disruption of metabolism of arachidonic acid and blockade of prostaglandin synthesis.

The anti-inflammatory effect is due to a decrease in capillary permeability (limits exudation), stabilization of lysosomal membranes (prevents the release of lysosomes enzymes that cause tissue damage), inhibition of synthesis or inactivation of inflammatory mediators (prostaglandins, histamine, bradykin, lymphokines, complement factors). Reduces the amount of free radicals in inflammation, inhibits chemotaxis and phagocytosis. Inhibits the proliferative phase of inflammation, reduces post-inflammatory tissue sclerosis; has a chondroprotective effect.

The drug reduces pain sensitivity in the focus of inflammation and acts on the thalamic centers of pain, has a desensitizing effect (with prolonged use). In rheumatic diseases reduces pain in the joints at rest and when moving, reduces morning stiffness and swelling of the joints, improves function and increases the volume of joint movements. 

Pharmacokinetics

Has a long half-life of 60-75 h. Easily passes through gistogematicalkie barriers, penetrates well into synovial fluid. Is characterized by a high bioavailability of 100%.

Indications for use

Inflammatory and degenerative diseases of musculoskeletal system, accompanied by pain syndrome:

  • gout arthritis, ankylosing spondylitis (Bekhterev’s disease);
  • infectious non-specific polyarthritis;
  • tendinitis, bursitis, myositis, periarthritis;
  • arthralgia, neuralgia, myalgia, sciatica, lumbago;
  • injuries, burns. 

Contraindications

  • hypersensitivity to tenoxicam or other NSAIDs;
  • erosive-ulcerative lesions of the gastrointestinal tract;
  • gastrointestinal bleeding;
  • pregnancy;
  • lactation;
  • childhood;
  • “aspirin triad»;
  • expressed disorders of liver and kidney function;
  • renal failure;
  • heart failure;
  • blood disease. 

Pregnancy and lactation

During pregnancy and lactation the drug should be administered with extreme caution, as there is no sufficient data on the use Artaxan in this category of patients.

Method of application and doses

Intended for intramuscular or intravenous administration.

Assigned at a dose of 20 mg once a day, maintaining dose: 10 mg per day.

With severe pain, you can increase the dose to 40 mg once a day.

In acute attacks of gout arthritis: 20 mg 2 times a day for the first 2-3 days, then 20 mg 1 time a day for 5 days.

Additional Information

SKU ml4675
Manufacturer Eipico
The purpose of the medication Oxicams
Weight kg. 0.1

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