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Drug Diane-35 refers to the pharmacological group of drugs oral contraceptives. It is used by women to prevent unwanted pregnancies, as well as to treat certain pathological conditions of the endocrine and reproductive system, accompanied by hormonal imbalances.
Pharmacological action of the drug is due to its active substances, which are modified female sex hormones. Cyproterone acetate is a modification of progesterone, and ethinyl estradiol is a representative of estrogen. In combination and with correct systematic use, these substances interfere with the process of fertilization of the ovum with sperm by suppressing the process of ovulation, changing the cervical canal (forming a mucus plug that prevents penetration of the uterus into the uterus of spermatozoa). Also, due to the effect of cyproterone on the sebaceous glands and the intensity of hair growth, the drug reduces the synthesis of sebum in acne (acne) and prevents the hormone induced weakening and hair loss.After taking the Diane-35 dragee, its active substances are absorbed quickly enough into the systemic bloodstream from the intestinal lumen. They are metabolized in the liver to the formation of inactive decay products, which are excreted from the body with urine (to a greater extent) and bile. On average, the half-life (the time during which half of the entire dose of the drug is excreted from the body) is 20 hours.
The main indication for the use of the Diana-35 dragee is contraception - prevention of unwanted pregnancy with unprotected sexual intercourse. Also, this drug is used in the complex treatment of acne vulgaris of moderate to severe severity.
Dragee Diana-35 is taken internally without chewing and drinking with a sufficient amount of water. The drug should be taken at the same time 1 time per day. The blister contains 21 dragees, which corresponds to the complete calendar cycle of taking the drug. In the package, each pills are marked with a specific day of the week, in which it should be taken, the sequence of reception is marked on the blister with a special arrow. For the purpose of contraception, the drug begins on the first day of the menstrual cycle (corresponding to the first day of the onset of menstruation). It is allowed to start taking the drug for 2-3 days from the beginning of the menstrual cycle, but during the first week it is necessary to protect against the onset of unwanted pregnancy with the help of barrier methods of contraception. After the end of the reception of the 21st tablet, a break takes 7 days. Then the reception of a new blister begins. In case of missed intake of the drug with a delay of no more than 12 hours, it must be taken as soon as possible, and the following dragees are taken in the same scheme and at the same time as always. If the delay of tablet more than 12 hours, then the woman can also take the following pills as soon as possible (even if it coincides with the reception of the next pills) or stop taking from the current blister stand 7 days break, and begin receiving the next blister from the first day . The break in taking the drug should not exceed 7 days. The length of the course of admission is determined by the woman's desire for protection from pregnancy.
To date, there is no evidence of an overdose of Diane-35 dragee. If the recommended therapeutic dose is exceeded, it is possible to develop side effects. In such cases, symptomatic therapy is used. There is no specific antidote.
The shelf life of the Diane-35 dragee is 5 years from the date of manufacture. The drug should be stored out of reach of children at an air temperature of not more than +30 ° C.'
|The purpose of the medication||Contraception|