GHRP-2 (Growth Hormone Releasing Peptide-2 and Somatotropin) is a growth hormone (somatotropin) stimulator which demonstrated high efficiency associated with sublingual and transbuccal administration in humans. GHRP-2 is probably the most potent booster (stimulator) of somatotropin secretion. GHRP-2 is an oligopeptide which can bypass liver by passing to blood flow through oral cavity blood vessels. According to studies, GHRP-2 stimulates pituitary gland inducing increase in somatotropin secretion by 7-15 times. At the same time, other GABA- and amino acid-based growth hormone stimulators raise this level not more than 2-3 times higher than baseline.
Growth Hormone Releasing Peptide-2 consists of 6 sequentially connected amino acids. The growth hormone stimulator is included in peptide group interacting with G protein-coupled hypothalamic and pituitary receptors. For the first time these peptides were derived from met-enkephalin (synthetic peptide) at the end of the last century. Although GHRP-2 has no structural similarity with somatotropin-releasing hormone (endogenic biologically active substance naturally inducing growth hormone secretion), it demonstrated similar pituitary effects during clinical trials.
As GHRP-2 has low molecular weight, it easily penetrates through well-vascularized mucosa of oral cavity providing means for avoiding parenteral administration. Efficiency and good tolerance of sublingual, intranasal and transbuccal administration methods are confirmed by medical trials.
According to clinical outcomes published in Journal of Endocrinology and Metabolism (1997), Growth Hormone Releasing Peptide-2 increases somatotropin secretion in children, adults and even in seniors.
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GHR Peptide-2 is the most potent and safe somatotropin secretion stimulator among all the commercially available ones. Its efficiency is comparable with growth hormone preparations and this fact is confirmed by several independent researches.
It should mixed gently with 5ml of water for injection and it should be injected using an insulin syringe either under the skin or between muscles. Studies demonstrated that GHRP-2 has dose-dependent effect (i.e., increase in somatotropin level depends directly on administered dose despite patient's sex, age and body fat percentage). In more recent times, another study conducted in children determined distinct relationship between growth hormone concentration and GHRP-2 dose.
In order to obtain certain effect, bodybuilders use GHRP-2 (0.001-0.002 mg/kg) for 2-3 times a day. In other words, average single dose for a bodybuilder is 0.1-0.2 mg. Typically, 2-3 subcutaneous injections (0.1-0.2 mg each) are given every day (15 minutes before food intake, after a workout and before bedtime). No adverse reactions were reported after administration of 1 mg for 2-3 times a day. However, you should not increase dosage because enhancement rate of peptide efficiency is substantially slower when dose is higher than 0.2 mg. Moreover, cortisol and prolactin levels may also rise.
GHRP-2 must be administered in at least 40-60 minutes after food intake. Then you must not eat carbohydrate- or lipid-containing foods after giving the injection. Theoretically, you should not eat anything. Food intake is allowed in 40 minutes when growth hormone release starts to decrease. Proteins (in particular, glutamine, arginine and D-aspartic acid) prolong this release.
It's appropriate to combine this peptide with CJC-1295 in order to achieve maximum (synergistic) effect and cost saving, as well as to solve desensitization issue.
Despite high transient increase in growth hormone level, short-term half-life of GHRP-2 is supposed to be responsible for absence of substantial increment in IGF-1 blood concentration. That's why this product should be combined with other peptides with longer half-life (e.g., CJC-1295). Supplements containing GHRP-2 should be combined with other growth hormone stimulators (e.g., arginine, GABA and glutamine) to achieve synergistic effect and to obtain considerably higher somatotropin level. This is a healthy combination.
Studies confirmed high GHRP-2 safety level and near-complete absence of GHRP-2-induced side effects. GHRP-2 is involved in clinical trials for more than 30 years. That's why long-term side effects can be also ruled out.
The MHRA and FDA has not evaluated or endorsed this product. Please consult your physician prior to using this or any other nutritional supplements or medications.
Storage at 2-8C degrees. Keep away from direct sunlight. Keep locked and away from children.
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