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An established deficiency of magnesium, isolated or associated with other deficient conditions, accompanied by symptoms such as increased irritability, minor sleep disorders, gastrointestinal spasms, palpitations, fatigue, pain and muscle spasms, a tingling sensation in the muscles. If, after a month of treatment with Magnelis B6 forte, there is no decrease in these symptoms, continued treatment is impractical.
- Hypersensitivity to any of the components of Magnelis B6 forte- severe renal failure (creatinine clearance less than 30 ml / min)- age up to 12 years (efficiency and safety ns established)- hereditary galactosemia, glucose malabsorption syndrome and galactose, or lactase deficiency (due to the presence of lactose monohydrate in the formulation)- simultaneous reception of levodopa.Carefully
Moderate renal failure (risk of hypermagnesemia).
The clinical experience of using a combination of magnesium citrate and pyridoxine hydrochloride in a sufficient number of pregnant women has not revealed any adverse effect on the onset of fetal developmental or fetotoxic effects. Can be used during pregnancy only if necessary, on the recommendation of a doctor.Taking into account that magnesium penetrates into the mothers milk, if it is necessary to take Magnelis B6 forte it is recommended to stop breastfeeding.
Tablets Magnelis B6 forte should be taken whole, washed down with a glass of water.Adults: 3-4 tablets per day, divided into 2-3 receptions, during meals.Children over the age of 12: 2-4 tablets per day, divided into 2-3 doses, with meals.Usually the duration of treatment with Magnelis B6 forte is one month.
Magnesium (as part of Magnelis B6 forte) is a vital element that is necessary for the normal functioning of cells, is involved in most metabolic reactions. In particular, it is involved in the regulation of the transmission of nerve impulses and in muscle contraction.50% of the amount of magnesium contained in the body accumulates in bone tissue.Pyridoxine (vitamin B6), which is part of Magnelis B6 Forte, participates in many metabolic processes, contributes to better absorption of magnesium from the gastrointestinal tract and its penetration into cells.Concentration of magnesium in serum:- between 12 and 17 mg / l (1 - 1.4 mEq / L or 0.5 - 0.7 mmol / L): indicates a moderate deficiency of magnesium- below 12 mg / l (1 mEq / L or 0.5 mmol / L): indicates a severe magnesium deficiency.The body gets magnesium along with the food. The lack of magnesium in the body can be observed with a deficiency in the intake or with an increase in the demand for magnesium.
Symptoms. With normal kidney function, an overdose of magnesium when ingested usually does not lead to the occurrence of toxic reactions. However, in the case of kidney failure, the development of magnesium poisoning is possible.Symptoms of overdose, the severity of which depends on the concentration of magnesium in the blood: lowering blood pressure nausea, vomiting depression of the central nervous system, decreased reflexes changes on the electrocardiogram oppressionrespiration, coma, cardiac arrest and respiratory paralysis aiurichesky syndrome.Treatment of an overdose Magnelis B6 forte.Rehydration, forced diuresis. With renal failure, hemodialysis or peritoneal dialysis is necessary.
It is intended only for adults and children over 12 years.The drug contains lactose monohydrate, therefore its use is not recommended for patients with hereditary galactosemia, glucose malabsorption syndrome and galactose, or lactase deficiency.With moderate renal failure, the drug should be taken with caution because of the risk of developing giermaggnini.With a simultaneous deficiency of calcium and magnesium, magnesium deficiency should be replenished before taking calcium supplements or dietary supplements containing calcium.When using pyridoxine at high doses (more than 200 mg per day) for a long time (for several months or in some cases, years) sensory axonal neuropathy can develop, which is accompanied by symptoms such as numbness and disturbance of proprioceptive sensitivity, tremor of the distal sections limbs and gradually developing sensory ataxia (impaired coordination of movements). These disorders are usually reversible and pass after stopping the intake of Magnelis B6 forte (and, as a consequence, stopping the intake of vitamin B6.
Contraindicated combinations Magnelis B6 forte.With levodopa: the activity of levodopa is inhibited by pyridoxine (if this drug is not combined with the reception of inhibitors of peripheral decarboxylase of aromatic L-amino acids). Any amount of pyridoxine should be avoided if levodopa is not taken in conjunction with inhibitors of the peripheral decarboxylase of aromatic L-amino acids.When appointing tetracyclines inside, it is necessary to observe an interval of at least three hours between admission, since magnesium preparations reduce the absorption of tetracyclines.Simultaneous use of drugs containing phosphates or calcium salts can impair the absorption of magnesium (the active ingredient Magnelis B6 forte) in the intestine.
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